In anticipation of the Gala Dinner on October 16, during which the official Award Ceremony will take place, we are pleased to share the strong interest and participation that have accompanied the Digital Innovation Forum - ComoLake Awards 2025, with numerous high-profile nominations received from across Europe. On this occasion, we would also like to recall the IMTAI Awards 2025, special recognitions granted by the International Multidisciplinary Task Force on AI Agents Intelligence, to two projects that exemplify the balance between technological progress and ethical responsibility. As we await the Award Ceremony, we are pleased to share once again the Nominations and winning projects, which represent some of the most promising directions in the European innovation landscape.

1. Networks and Infrastructures, Mobility and Transport, Energy and Sustainability

• Nomination 1: ID 28054 - SHIELD IT REPLY (Shield Reply - Reply Group)
  Motivation: SHIELD IT REPLY introduces an innovative cybersecurity and data protection solution for distributed environments, integrating AI for real-time threat detection, advanced encryption, and secure management in hybrid cloud and edge computing systems. Compared to traditional solutions, it reduces vulnerabilities and response times through a modular approach that ensures compliance with EU regulations. Feasible and already deployed in critical infrastructures, it is scalable at the European level and has a strategic impact on national resilience, reducing cyber risks and supporting the country's digital transition in line with the PNRR. Results show a 30% reduction in incidents, sectoral leadership within the Reply Group, strategic development with a focus on internationalization, high service quality, environmental sustainability through cloud resource optimization, and continuous operator training.

• Nomination 2: ID 26588 - IBM Quantum Lake (IBM Italia S.p.A.)
  Motivation: IBM Quantum Lake is a training and experimentation program on quantum computing, with educational and technological impact on the national ecosystem. It integrates practical simulations, laboratories, and collaborations with universities to develop expertise in quantum algorithms applied to networks, infrastructures, and energy sustainability. Innovative for its hands-on approach on IBM Quantum platforms, it is feasible with accessible cloud resources and scalable at both educational and industrial levels. It contributes to sectoral innovation by accelerating research in network optimization and complex simulations, with a qualitative impact on the country through talent development and reduction of the technological gap. Results include hundreds of trained participants (2024-2025), IBM’s sectoral leadership in quantum computing, strategic development through EU partnerships, international expansion via global programs, high service quality, sustainability through quantum energy efficiency, and advanced training for the national ecosystem.

• Nomination 3: ID 29832 - Lutech (Lutech Group)
  Motivation: Lutech’s project introduces end-to-end digital solutions for networks and infrastructures, integrating AI, IoT, and cloud technologies to optimize mobility, transport, and energy sustainability, with a focus on smart grids and predictive monitoring systems. Innovative for its multi-platform integration, it is feasible for industrial implementation and scalable nationally and internationally. It contributes strategically to the country’s development by reducing energy consumption and improving infrastructure efficiency, in line with ESG and PNRR goals. Company results demonstrate growth in partnerships, sectoral leadership in digital transformation, strategic development focused on R&D, European internationalization, high service quality, environmental sustainability, and professional upskilling programs.

2. Banking, Insurance e Fintech

• Nomination 1: ID 30607 - INAIL - Progetto Archimede (INAIL)
  Motivation: Archimede is an AI-based system for fraud prevention, distinguished by its circular approach and compliance with ISO 42001 standards. It is already implemented within public administration, feasible, and scalable thanks to its open-source and interoperable architecture. The project delivers significant social impact by promoting legality and efficient use of public resources, establishing INAIL’s leadership in digital public administration. The documentation is of high quality, with strong emphasis on AI ethics and sustainability.

3. Public Sector

• Nomination 1: ID 27046 - Piattaforma di Business Intelligence e Artificial Intelligence per la Giustizia amministrativa (Consiglio di Stato - Segretariato generale della Giustizia Amministrativa)
  Motivation: This platform introduces innovation in the judicial sector through a Data Warehouse containing over 20 million documents, integrated with Business Intelligence and Artificial Intelligence tools for semantic search, anonymization of rulings, and identification of similar appeals, as well as 5-star linked open data. Completed with PNRR funding, it is fully realizable and scalable, with future developments including predictive analysis, Geo-Analytics, and extension to 33 Regional Administrative Courts (TAR). The project ensures cyber-resilience and algorithmic explainability. Its socio-economic impact is significant, improving governance efficiency, reducing judicial times, and promoting civic transparency and environmental sustainability through energy-efficient cloud infrastructures and AI quantization, in line with constitutional principles.

• Nomination 2: ID 27042 - App YouPol (Ministero dell’Interno - Dipartimento della Pubblica Sicurezza - Polizia di Stato)
  Motivation: YouPol innovates the public sector through an anonymous real-time reporting system with selective geolocation and multilingual support to prevent bullying, drug trafficking, and domestic violence, redefining digital proximity between citizens and institutions. Fully scalable, with an AI roadmap for predictive analysis and PA integration, the project delivers measurable socio-economic impact - increasing individual security by 30%, reducing common crimes, and strengthening public trust in the State, in alignment with e-government strategies and the PNRR. The results, validated by schools and academic institutions during 2024-2025, highlight its pioneering role in participatory safety. The high-quality documentation underscores cloud-based sustainability (lower costs and CO₂ emissions), digital awareness training for students and families, and EU-level scalability for future e-safety collaborations.

4. Sanità

• Nomination 1: ID 29788 - AI driven Discovery of Novel Antibiotics (TaccLab, Università di Padova)
  Motivation: The project leverages artificial intelligence to accelerate the discovery of new antibiotics, integrating open-source language models, molecular screening, and automated patent verification. Its innovative approach applies Large Language Models (LLMs) to pharmacology, reducing research time and costs while addressing the global antibiotic resistance crisis. Already operational within TaccLab laboratories, the project includes in vitro testing, the creation of an academic spin-off, and the development of a scalable cloud architecture with international reach. It promotes Italian technological sovereignty, the training of professionals in the fields of AI and biotechnology, and the adoption of green chemistry principles for more sustainable research. With a strategic impact on both the healthcare and industrial systems, the project strengthens Italy’s leadership in AI applied to health and drug discovery.

• Nomination 2: ID 29236 - Infant (Innovaway con Università di Napoli “Federico II”, DIETI - Laboratorio Astrea) 
  Motivation: The Innovaway project, under the scientific responsibility of the University of Naples “Federico II”, DIETI - Astrea Laboratory, introduces digital solutions for healthcare by integrating AI for patient management, telemedicine, and predictive analytics. These innovations optimize operational workflows in hospitals and long-term care facilities (RSA). The Infant project aims to enhance the quality and efficiency of pediatric oncology services, ensuring continuity of care and optimizing healthcare resources through the adoption of advanced technologies. Innovative for its end-to-end approach, the project can be implemented within healthcare structures and scaled nationally. It contributes to a qualitative impact on the country’s healthcare system by improving the efficiency of the National Health Service (SSN), reducing waiting times, and promoting personalized care, in line with the objectives of the PNRR (National Recovery and Resilience Plan). Corporate results highlight successful adoption in pilot projects, leadership in health IT, strategic growth through partnerships and internationalization, and a strong focus on service quality and sustainability-achieved through resource optimization and training programs for healthcare professionals on digital tools.

• Nomination 3: ID 27035 - X-RAIS (Laife Reply)
  Motivation: X-RAIS revolutionizes mammographic diagnostics through agentic AI, neural networks, and radiomics, natively integrating with PACS/RIS systems to enable precise detection of suspicious lesions and explainable visual interpretations. Clinically validated in European Radiology Experimental and tested at IEO, the solution is fully realizable and scalable both nationally and internationally, in compliance with GDPR and the AI Act. The socio-economic impact is significant - reducing diagnostic variability, enabling earlier breast cancer detection, and optimizing healthcare costs, in alignment with the PNRR’s digital health objectives.

3Bee

3Bee applies IoT sensors and machine learning models to monitor biological and climatic conditions in ecosystems.
The platform integrates predictive analytics and data fusion to assess biodiversity in real time.
Collected data generate quantitative environmental health indicators that can be used within ESG frameworks.
Its architecture is scalable, interoperable, and scientifically validated.
The project combines engineering rigor with measurable ecological impact and represents a European benchmark in NatureTech applied to territorial regeneration.

Aike

Aike uses multimodal AI models to analyze and predict real purchasing behaviors.
It combines transaction data, digital footprints, and socio-economic context within a single predictive architecture.
The platform provides real-time insights for strategic marketing and retail planning.
It is compliant with data ethics principles and privacy-by-design standards.
Aike serves as a European benchmark for evidence-based behavioral analysis.

Ogyre

Ogyre implements a circular model for marine waste recovery based on a global “fishing for litter” network.
It integrates digital tracking, material cataloging, and environmental impact metrics.
The collected data are analyzed to optimize logistics and recycling in real time.
The system is scalable at a global ocean level and is already operational across multiple continents.
Ogyre represents a synthesis of technology, circular economy, and advanced environmental monitoring.

FloFleet

FloFleet designs and develops autonomous electric aerostats powered by solar energy, intended for environmental and infrastructure monitoring.
The architecture integrates intelligent control systems, multispectral sensors, and AI-assisted stabilization algorithms.
These aircraft can operate continuously for several days, drastically reducing costs and emissions compared to conventional drones.
The platform enables survey, surveillance, and communication missions in areas difficult to reach with traditional means.
FloFleet represents an advanced combination of aerospace engineering, renewable energy, and intelligent automation.

Four projects, four distinct paths converging toward a single goal: technological innovation as a tool for regeneration, knowledge, and sustainability.
3Bee, Aike, Ogyre, and FloFleet represent the new generation of European enterprises combining scientific research, advanced engineering, and environmental responsibility.
From biodiversity monitored with sensors and predictive algorithms, to intelligent analysis of human behavior, marine waste recovery, and autonomous flight systems for territorial monitoring, these projects demonstrate how AI, data, and automation can create tangible, measurable impact.
Three out of four rely on artificial intelligence as the core of their technological architecture, confirming that AI is no longer a separate sector but a transversal driver of transformation.
Together, they embody a business model that does not pit progress against sustainability, but merges them into a single vision: innovation capable of improving the planet, understanding people, and shaping the future.

The International Multidisciplinary Task Force on AI Agents Intelligence (IMTAI) has awarded the AI 2025 Prizes to two projects that exemplify the convergence of technological innovation and ethical responsibility: AI-IstatData and Yiami - Cognitive Experience Platform.

Both initiatives are tangible examples of how the principles outlined in the IMTAI Manifesto on Artificial Intelligence - Classification as Foundation, Risk as Metric, Technological Humanism - can be translated into operational, measurable, and sustainable architectures.

The vector-based semantic infrastructure was designed in compliance with Istat’s data security and protection policies, integrating open AI models in a cautious, verifiable, and human-supervised manner.

The project is now considered a European benchmark for digital public administration, and an operational model for transforming public data into validated, accessible knowledge.

Thanks to this vision, Yiami positions itself as a new paradigm of human-centered AI, uniting generative power, cognitive sustainability, and operational transparency.