Digital Innovation Forum - ComoLake Awards 2025 celebrate the most outstanding projects that, through the adoption of enabling technologies such as Artificial Intelligence, Quantum Computing, Cybersecurity, and Blockchain, generate a tangible, measurable, and replicable impact across economic, social, and institutional sectors. The Awards also emphasize ethics and sustainability, promoting scalable and forward-looking solutions, in accordance with the Official Regulations, which define the participation and evaluation criteria.

The Jury, composed of members of the Scientific Committee of the Fondazione Innovazione Digitale ETS, evaluated the applications received by October 7, 2025, based on criteria such as innovation, feasibility, scalability, socio-economic impact, and the quality of the submitted documentation. 3 Nominations were selected for each of the four thematic areas, according to the regulations, with the option to assign special mentions or cross-category recognitions.

For Innovative Startups, a Best Startup Award is granted in each area, evaluated also on the basis of the number of clients, revenue growth, and funding received.

The composition of the Scientific Committee includes the following members, along with their respective roles and affiliations:

• Prof. Francesco Saverio Cataliotti: President of the Scientific Committee of the Fondazione Innovazione Digitale; Director of the National Institute of Optics at the National Research Council.

• Dr.ssa Mariella Enoc: Former President of the Bambino Gesù Hospital; Special Prosecutor of the Valduce Hospital in Como.

• Prof. Antonio La Gatta: Electronic Engineer; Adjunct Professor at various Italian and international universities.

• Dott. Davide Costa: IT Engineer and backend developer with expertise in IT infrastructures, databases, security systems, and networking; serial entrepreneur, blockchain enthusiast, and founder of Foodchain.

• Prof.ssa Paola Dubini: President of Fondazione Alessandro Volta; Professor of Management at Bocconi University.

• Dr. Tom Darden: Founder Cherokee Investment Partner, CEO IH Fusion.

• Prof. Vincenzo Vespri: Professor of Mathematical Analysis at the University of Florence.

• Dott. Paolo Branchini: Senior Researcher at the National Institute for Nuclear Physics (INFN), Roma Tre University; Member of the Quantum Technologies Coordination Group Panel.

• Dr. Denis Bron: MD, University of Basel.

• Dott. Daniele Invernizzi: President of the eV-Now! Foundation for Electric Mobility and Founder of Tesla Owners Italia.

The Committee is responsible for guiding the content of the Forum and determining the winners of the Awards, ensuring an ethical and sustainability-oriented approach in line with the objectives set forth in the Regulations.

Below is the list of selected nominations, grouped by thematic area, along with their respective motivations. The winners will be announced during the awards ceremony on October 16, 2025, at Villa Erba in Cernobbio, during the Forum’s closing gala evening, as stated in the Regulations (Page 3).

1. Networks and Infrastructures, Mobility and Transport, Energy and Sustainability

• Nomination 1: ID 28054 - SHIELD IT REPLY (Shield Reply - Reply Group)
  Motivation: SHIELD IT REPLY introduces an innovative cybersecurity and data protection solution for distributed environments, integrating AI for real-time threat detection, advanced encryption, and secure management in hybrid cloud and edge computing systems. Compared to traditional solutions, it reduces vulnerabilities and response times through a modular approach that ensures compliance with EU regulations. Feasible and already deployed in critical infrastructures, it is scalable at the European level and has a strategic impact on national resilience, reducing cyber risks and supporting the country's digital transition in line with the PNRR. Results show a 30% reduction in incidents, sectoral leadership within the Reply Group, strategic development with a focus on internationalization, high service quality, environmental sustainability through cloud resource optimization, and continuous operator training.

• Nomination 2: ID 26588 - IBM Quantum Lake (IBM Italia S.p.A.)
  Motivation: IBM Quantum Lake is a training and experimentation program on quantum computing, with educational and technological impact on the national ecosystem. It integrates practical simulations, laboratories, and collaborations with universities to develop expertise in quantum algorithms applied to networks, infrastructures, and energy sustainability. Innovative for its hands-on approach on IBM Quantum platforms, it is feasible with accessible cloud resources and scalable at both educational and industrial levels. It contributes to sectoral innovation by accelerating research in network optimization and complex simulations, with a qualitative impact on the country through talent development and reduction of the technological gap. Results include hundreds of trained participants (2024-2025), IBM’s sectoral leadership in quantum computing, strategic development through EU partnerships, international expansion via global programs, high service quality, sustainability through quantum energy efficiency, and advanced training for the national ecosystem.

• Nomination 3: ID 29832 - Lutech (Lutech Group)
  Motivation: Lutech’s project introduces end-to-end digital solutions for networks and infrastructures, integrating AI, IoT, and cloud technologies to optimize mobility, transport, and energy sustainability, with a focus on smart grids and predictive monitoring systems. Innovative for its multi-platform integration, it is feasible for industrial implementation and scalable nationally and internationally. It contributes strategically to the country’s development by reducing energy consumption and improving infrastructure efficiency, in line with ESG and PNRR goals. Company results demonstrate growth in partnerships, sectoral leadership in digital transformation, strategic development focused on R&D, European internationalization, high service quality, environmental sustainability, and professional upskilling programs.

2. Banking, Insurance e Fintech

• Nomination 1: ID 30607 - INAIL - Progetto Archimede (INAIL)
  Motivation: Archimede is an AI-based system for fraud prevention, distinguished by its circular approach and compliance with ISO 42001 standards. It is already implemented within public administration, feasible, and scalable thanks to its open-source and interoperable architecture. The project delivers significant social impact by promoting legality and efficient use of public resources, establishing INAIL’s leadership in digital public administration. The documentation is of high quality, with strong emphasis on AI ethics and sustainability.

3. Public Sector

• Nomination 1: ID 27046 - Piattaforma di Business Intelligence e Artificial Intelligence per la Giustizia amministrativa (Consiglio di Stato - Segretariato generale della Giustizia Amministrativa)
  Motivation: This platform introduces innovation in the judicial sector through a Data Warehouse containing over 20 million documents, integrated with Business Intelligence and Artificial Intelligence tools for semantic search, anonymization of rulings, and identification of similar appeals, as well as 5-star linked open data. Completed with PNRR funding, it is fully realizable and scalable, with future developments including predictive analysis, Geo-Analytics, and extension to 33 Regional Administrative Courts (TAR). The project ensures cyber-resilience and algorithmic explainability. Its socio-economic impact is significant, improving governance efficiency, reducing judicial times, and promoting civic transparency and environmental sustainability through energy-efficient cloud infrastructures and AI quantization, in line with constitutional principles.

• Nomination 2: ID 27042 - App YouPol (Ministero dell’Interno - Dipartimento della Pubblica Sicurezza - Polizia di Stato)
  Motivation: YouPol innovates the public sector through an anonymous real-time reporting system with selective geolocation and multilingual support to prevent bullying, drug trafficking, and domestic violence, redefining digital proximity between citizens and institutions. Fully scalable, with an AI roadmap for predictive analysis and PA integration, the project delivers measurable socio-economic impact - increasing individual security by 30%, reducing common crimes, and strengthening public trust in the State, in alignment with e-government strategies and the PNRR. The results, validated by schools and academic institutions during 2024-2025, highlight its pioneering role in participatory safety. The high-quality documentation underscores cloud-based sustainability (lower costs and CO₂ emissions), digital awareness training for students and families, and EU-level scalability for future e-safety collaborations.

4. Sanità

• Nomination 1: ID 29788 - AI driven Discovery of Novel Antibiotics (IBM con Università di Padova)
  Motivation: The AI-driven Discovery of Novel Antibiotics project leverages Artificial Intelligence and quantum computing to accelerate the discovery of new antibiotics, tackling antimicrobial resistance through advanced molecular modeling and virtual screening within Tasclab. Innovative in its integration of quantum computing, the project is feasible through academic–industrial collaboration and preclinical testing, and globally scalable via IBM platforms. Its strategic national impact strengthens biomedical research, reduces costs linked to resistant infections, and promotes technological sovereignty in biotech, in line with WHO and PNRR goals. Results include the identification of promising candidates, IBM’s leadership in healthcare AI, strategic development focused on R&D, international partnerships across the EU, high service quality, environmental sustainability through reduced animal testing, and researcher training in quantum tools.

• Nomination 2: ID 29236 - Innovaway
  Motivation: Innovaway introduces digital solutions for healthcare, integrating AI for patient management, telemedicine, and predictive analytics to streamline hospital and long-term care operations. Innovative in its end-to-end approach, the project is realizable with implementations in healthcare facilities and scalable nationwide. It delivers a qualitative impact on the national healthcare system by increasing efficiency, reducing waiting times, and promoting personalized care in line with the PNRR. Company results highlight adoption in pilot projects, leadership in healthcare IT, strategic development through partnerships and internationalization, high service quality, sustainability via optimized resource use, and training programs for healthcare professionals on digital tools.

• Nomination 3: ID 27035 - X-RAIS (Laife Reply)
  Motivation: X-RAIS revolutionizes mammographic diagnostics through agentic AI, neural networks, and radiomics, natively integrating with PACS/RIS systems to enable precise detection of suspicious lesions and explainable visual interpretations. Clinically validated in European Radiology Experimental and tested at IEO, the solution is fully realizable and scalable both nationally and internationally, in compliance with GDPR and the AI Act. The socio-economic impact is significant - reducing diagnostic variability, enabling earlier breast cancer detection, and optimizing healthcare costs, in alignment with the PNRR’s digital health objectives.

3Bee

3Bee applies IoT sensors and machine learning models to monitor biological and climatic conditions in ecosystems.
The platform integrates predictive analytics and data fusion to assess biodiversity in real time.
Collected data generate quantitative environmental health indicators that can be used within ESG frameworks.
Its architecture is scalable, interoperable, and scientifically validated.
The project combines engineering rigor with measurable ecological impact and represents a European benchmark in NatureTech applied to territorial regeneration.

Aike

Aike uses multimodal AI models to analyze and predict real purchasing behaviors.
It combines transaction data, digital footprints, and socio-economic context within a single predictive architecture.
The platform provides real-time insights for strategic marketing and retail planning.
It is compliant with data ethics principles and privacy-by-design standards.
Aike serves as a European benchmark for evidence-based behavioral analysis.

Ogyre

Ogyre implements a circular model for marine waste recovery based on a global “fishing for litter” network.
It integrates digital tracking, material cataloging, and environmental impact metrics.
The collected data are analyzed to optimize logistics and recycling in real time.
The system is scalable at a global ocean level and is already operational across multiple continents.
Ogyre represents a synthesis of technology, circular economy, and advanced environmental monitoring.

FloFleet

FloFleet designs and develops autonomous electric aerostats powered by solar energy, intended for environmental and infrastructure monitoring.
The architecture integrates intelligent control systems, multispectral sensors, and AI-assisted stabilization algorithms.
These aircraft can operate continuously for several days, drastically reducing costs and emissions compared to conventional drones.
The platform enables survey, surveillance, and communication missions in areas difficult to reach with traditional means.
FloFleet represents an advanced combination of aerospace engineering, renewable energy, and intelligent automation.

Four projects, four distinct paths converging toward a single goal: technological innovation as a tool for regeneration, knowledge, and sustainability.
3Bee, Aike, Ogyre, and FloFleet represent the new generation of European enterprises combining scientific research, advanced engineering, and environmental responsibility.
From biodiversity monitored with sensors and predictive algorithms, to intelligent analysis of human behavior, marine waste recovery, and autonomous flight systems for territorial monitoring, these projects demonstrate how AI, data, and automation can create tangible, measurable impact.
Three out of four rely on artificial intelligence as the core of their technological architecture, confirming that AI is no longer a separate sector but a transversal driver of transformation.
Together, they embody a business model that does not pit progress against sustainability, but merges them into a single vision: innovation capable of improving the planet, understanding people, and shaping the future.